great change
definitions
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A profound, significant, or transformative shift in social, political, personal, or environmental circumstances.zh: 重大变革
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A substantial difference in quantity, degree, magnitude, or scale.zh: 巨大的差异
examples
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Wise men and women spoke of a great change coming, of a new ruler who would rise from the west to overthrow the tyrant.
智者们谈论着即将到来的重大变革,谈论着一位将从西方崛起并推翻暴君的新统治者。
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The experiment resulted in a great change in the chemical composition of the substance.
该实验导致物质的化学成分发生了巨大变化。