final devastating loss
definitions
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A concluding defeat, failure, or destruction that is extremely overwhelming and causes irreparable damage.zh: 最终毁灭性失败
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The ultimate death or passing of a loved one that results in profound and overwhelming grief.zh: 最终痛心丧亲
examples
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The company's bankruptcy was the final devastating loss for the investors.
公司的破产是投资者最终的毁灭性损失。
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Losing his wife after years of illness was his final devastating loss.
在多年的病痛之后失去妻子是他最终令人痛心的丧亲。