catastrophic personal and societal destruction
definitions
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The state of extreme, widespread ruin affecting both the lives and well-being of individuals and the fundamental structures, stability, and order of a society.zh: 个人与社会的毁灭性破坏
examples
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The sudden outbreak of the plague led to catastrophic personal and societal destruction.
瘟疫的突然爆发导致了个人与社会的毁灭性破坏。