profound existential dread
definitions
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An intense, overwhelming feeling of anxiety or fear concerning the fundamental nature of existence, the meaning of life, or the inevitability of death.ja: 深い実存的恐怖
examples
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Staring at the vast, empty cosmos, he was overcome by a sense of profound existential dread.
広大で空虚な宇宙を見つめながら、彼は深い実存的恐怖に襲われた。