deep sin
definitions
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A moral transgression or wrongdoing that is considered extremely grave, profound, or spiritually damaging.fr: Péché grave
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A sin that is deeply ingrained, habitual, or carries a heavy psychological burden of guilt.fr: Péché profondément enraciné
examples
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He believed that his deep sin would prevent him from finding peace.
Il croyait que son péché profond l'empêcherait de trouver la paix.
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The artist struggled with the deep sin of his past actions throughout his life.
L'artiste a lutté toute sa vie contre le péché profond de ses actes passés.