fundamental problem
definitions
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A basic, central, or essential issue that lies at the root of a situation, system, or conflict.es: Problema esencial
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A deep-seated difficulty or contradiction within the theoretical, logical, or scientific basis of a field of study.es: Problema teórico
examples
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The lack of funding is the fundamental problem facing the project.
La falta de financiación es el problema fundamental que enfrenta el proyecto.
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Quantum mechanics presents a fundamental problem for classical physics.
La mecánica cuántica plantea un problema teórico para la física clásica.